Venom peptides as inhibitory agents against flaviviral proteases

• Main Author: Cai, Maggie Weiling
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/45102
• Institution: Nanyang Technological University

Due to the lack of vaccines and effective therapies, infectious diseases caused by members of the Flaviviridae family pose a major healthcare concern worldwide. The nonstructural protein 3(NS3) is multifunctional, with serine protease activity in its N-terminal domain, RNA triphosphatase and helica...