Activation and regulation of IL-1β in dengue virus

• Main Author: Nafisah Zakariah
• Other Authors: Liu Ding Xiang
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/45107
• Institution: Nanyang Technological University

Dengue virus can elicit a spectrum of clinical manifestations from the mild dengue fever to severe dengue haemorrhagic fever and septic shock. To date, no effective vaccines exist. A hallmark characteristic of DENV is plasma leakage and liver damage. Elevated inflammatory response by our innate immu...