Decorating dsDNA with a functional belt : bisAGT zif-finger protein for site-specific tagging of DNA.

• Main Author: Pham Song Khanh Hang.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/45128
• Institution: Nanyang Technological University

Being the best understood DNA binding proteins, Zinc finger proteins can recognize and discriminate closely related sequences in both vitro and vivo (Klug, 2010). This ability has made them to be a promising candidate in creating a system that can detect DNAs in their native forms. In more than two...