Immune-factors regulating the development of experimental cerebral malaria in mice infected or coinfected with Plasmodium spp.

• Main Author: Teo, Shun Xie.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/45265
• Institution: Nanyang Technological University

During malaria infection, innate responses are triggered to limit the maximum parasite density when it crosses certain threshold. Toll-like receptors signaling pathway, mononuclear phagocytes and NK cell-mediated cytotoxicity are known to have important roles in activation of protective innate immun...