Characterisation of ant-1 as an inhibitor of myostatin activity.

• Main Author: Irfana Begum Ikbal.
• Other Authors: Ravi Kambadur
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/45741
• Institution: Nanyang Technological University

Ant-1 is a mimetic peptide of the mature C-terminal region of Myostatin. It has previously been demonstrated to have Myostatin antagonistic activity as proven by increasing satellite cell activation and macrophage infiltration during skeletal muscle regeneration. Furthermore, Ant-1 also increased my...