Computational analysis of ChIP-seq data and its application to the reconstruction of transcriptional regulatory networks

• Main Author: Xu, Han
• Other Authors: Lin Feng
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences; DRNTU::Science::Biological sciences::Biomathematics
• Online Access: https://hdl.handle.net/10356/45765
• Institution: Nanyang Technological University

On benefit of the rapid growth of ultra-high-throughput sequencing technologies in recent years, ChIP-seq (Chromatin Immuno-Precipitation Sequencing) has become the main stream for the genome-wide study of protein-DNA interactions and histone modifications. Large amount of ChIP-seq datasets have bee...