Organocatalytic asymmertric reactions : aminoxylation, Michael and their tandem reactions

• Main Author: Chua, Pei Juan
• Other Authors: Zhong Guofu
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• Online Access: https://hdl.handle.net/10356/46227
• Institution: Nanyang Technological University

A highly enantioselectve L-thiaprolnie-catalysed a-aminoxylation of aldehydes in the presence of water and tertrabutylammonium bromide followed by in situ reduction to afford the respective a-aminoxy alcohols in good to high yields and excellent enantioselectivities was first developed.