Synthesis of bioactive amino acid building blocks and their applications towards the peptides and glycopeptides

• Main Author: Pasunooti, Kalyan Kumar
• Other Authors: Liu Xuewei
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Chemistry::Biochemistry
• Online Access: https://hdl.handle.net/10356/46460
• Institution: Nanyang Technological University

Since the discovery of native chemical ligation (NCL) by Kent and coworkers in 1994, the field of peptide synthesis has been achieved significant advancement over the last two decades. This study demonstrated that the reaction undergoes a chemoselective ligation with unprotected peptides and protein...