In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.

36 p.

Saved in:

Bibliographic Details
Main Author:	Sze, Siu Kwan.
Other Authors:	School of Biological Sciences
Format:	Research Report
Published:	2011
Subjects:	DRNTU::Science::Biological sciences
Online Access:	http://hdl.handle.net/10356/46702
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Nanyang Technological University

id	sg-ntu-dr.10356-46702
record_format	dspace
spelling	sg-ntu-dr.10356-467022023-02-28T17:58:29Z In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer. Sze, Siu Kwan. School of Biological Sciences DRNTU::Science::Biological sciences 36 p. We have developed a novel hydroxyl radical footprinting (HRF) technique for studying in vivo structural dynamic in membrane proteins in their native biological states on the cell surface. We have successfully applied the technique to elucidate the voltage gating mechanism of porin, an integral membrane protein, of E coli directly on the living cell. We further extended the method to study in-vivo structure dynamic of integrin aLp2 heterodimer, a pair of important membrane proteins of mammalian cell related to many human diseases. ARC 8/07 2011-12-21T05:14:41Z 2011-12-21T05:14:41Z 2010 2010 Research Report http://hdl.handle.net/10356/46702 Nanyang Technological University application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
topic	DRNTU::Science::Biological sciences
spellingShingle	DRNTU::Science::Biological sciences Sze, Siu Kwan. In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
description	36 p.
author2	School of Biological Sciences
author_facet	School of Biological Sciences Sze, Siu Kwan.
format	Research Report
author	Sze, Siu Kwan.
author_sort	Sze, Siu Kwan.
title	In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
title_short	In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
title_full	In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
title_fullStr	In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
title_full_unstemmed	In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.
title_sort	in-vivo structure-based studies on epidermal growth factor receptor (egfr) signalling in cancer.
publishDate	2011
url	http://hdl.handle.net/10356/46702
_version_	1759857009574805504

In-vivo structure-based studies on epidermal growth factor receptor (EGFR) signalling in cancer.

Similar Items