Oxygen transport and cell distribution of smooth muscle construct cultured under flow
311 p.
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2011
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| Institution: | Nanyang Technological University |
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sg-ntu-dr.10356-472012023-03-11T17:26:55Z Oxygen transport and cell distribution of smooth muscle construct cultured under flow Chan, Wing Yue Heng Chee Hoon School of Mechanical and Aerospace Engineering DRNTU::Engineering::Bioengineering 311 p. Internal oxygen transport is important in the development of tissue construct in vitro. A new bioreactor culture system and a mathematical model were established to investigate oxygen transport in relation to cell distribution of esophageal smooth muscle tissue construct cultured under medium flow. The bioreactor system was designed to enable in-situ oxygen profiling in the flow bioreactors to capture real-time spatial oxygen data in the growing construct; the mathematical model assuming oxygen-dependent growth kinetics was formulated using Volume Averaging Method (VAM) for the transport phenomena in the multiphasic tissue construct. DOCTOR OF PHILOSOPHY (MAE) 2011-12-27T06:35:21Z 2011-12-27T06:35:21Z 2010 2010 Thesis Chan, W. Y. (2010). Oxygen transport and cell distribution of smooth muscle construct cultured under flow. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47201 10.32657/10356/47201 Nanyang Technological University application/pdf |
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Nanyang Technological University |
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NTU Library |
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Asia |
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Singapore Singapore |
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DRNTU::Engineering::Bioengineering |
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DRNTU::Engineering::Bioengineering Chan, Wing Yue Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| description |
311 p. |
| author2 |
Heng Chee Hoon |
| author_facet |
Heng Chee Hoon Chan, Wing Yue |
| format |
Theses and Dissertations |
| author |
Chan, Wing Yue |
| author_sort |
Chan, Wing Yue |
| title |
Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| title_short |
Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| title_full |
Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| title_fullStr |
Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| title_full_unstemmed |
Oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| title_sort |
oxygen transport and cell distribution of smooth muscle construct cultured under flow |
| publishDate |
2011 |
| url |
https://hdl.handle.net/10356/47201 |
| _version_ |
1761781913264062464 |