Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots

79 p.

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Bibliographic Details
Main Author: Han Tun Aung
Other Authors: Subramanian Venkatraman
Format: Theses and Dissertations
Published: Popular Science 2011
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Online Access:http://hdl.handle.net/10356/47229
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-472292023-03-11T17:03:01Z Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots Han Tun Aung Subramanian Venkatraman School of Mechanical and Aerospace Engineering DRNTU::Engineering 79 p. In this research work, a novel controlled drug delivery system was studied. The system is made up of water insoluble, biodegradable polymers; poly (D,L lactide) (PDLLA) and poly (D,L-lactide-co-glycolide) (PLGA), dissolved in N-methyl-2-pyrrolidone (NMP). Such a polymer solution forms gel depot upon injection into the body fluids and the depot itself gradually degrades with time. A highly potent drug, 5-fluorouracil (5-FU) is incorporated into the depot to achieve the sustainable release profile. Master of Science (Biomedical Engineering) 2011-12-27T06:39:16Z 2011-12-27T06:39:16Z 2009 2009 Thesis http://hdl.handle.net/10356/47229 Nanyang Technological University application/pdf Popular Science
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Engineering
spellingShingle DRNTU::Engineering
Han Tun Aung
Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
description 79 p.
author2 Subramanian Venkatraman
author_facet Subramanian Venkatraman
Han Tun Aung
format Theses and Dissertations
author Han Tun Aung
author_sort Han Tun Aung
title Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
title_short Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
title_full Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
title_fullStr Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
title_full_unstemmed Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
title_sort drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
publisher Popular Science
publishDate 2011
url http://hdl.handle.net/10356/47229
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