Studies on the inhibition of viral entry of flaviviruses
166 p.
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Theses and Dissertations |
| Published: |
2011
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/47444 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| id |
sg-ntu-dr.10356-47444 |
|---|---|
| record_format |
dspace |
| spelling |
sg-ntu-dr.10356-474442023-02-28T18:47:00Z Studies on the inhibition of viral entry of flaviviruses Ravikumar Rajamanonmani Julien Lescar School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology 166 p. Dengue virus serotypes 1-4 (DENV1-4) cause serious febrile illness in humans, including Dengue haemorrhagic fever (DHF) and Dengue shock syndrome (DSS). Presence of avid neutralizing antibodies during clinical illness is critical in the outcome of clinical disease and severity of manifestations. Presently there are no specific anti-flaviviral therapeutic agents or an effective vaccine available for clinical use. In the current study, the possibilities of using the DENV envelope protein domain III (Ed3), as it possesses receptor binding activity, as a possible competitor to whole virus for entry into host cell receptor was explored. DOCTOR OF PHILOSOPHY (SBS) 2011-12-27T08:17:50Z 2011-12-27T08:17:50Z 2010 2010 Thesis Ravikumar Rajamanonmani. (2010). Studies on the inhibition of viral entry of flaviviruses. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47444 10.32657/10356/47444 Nanyang Technological University application/pdf |
| institution |
Nanyang Technological University |
| building |
NTU Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NTU Library |
| collection |
DR-NTU |
| topic |
DRNTU::Science::Biological sciences::Microbiology |
| spellingShingle |
DRNTU::Science::Biological sciences::Microbiology Ravikumar Rajamanonmani Studies on the inhibition of viral entry of flaviviruses |
| description |
166 p. |
| author2 |
Julien Lescar |
| author_facet |
Julien Lescar Ravikumar Rajamanonmani |
| format |
Theses and Dissertations |
| author |
Ravikumar Rajamanonmani |
| author_sort |
Ravikumar Rajamanonmani |
| title |
Studies on the inhibition of viral entry of flaviviruses |
| title_short |
Studies on the inhibition of viral entry of flaviviruses |
| title_full |
Studies on the inhibition of viral entry of flaviviruses |
| title_fullStr |
Studies on the inhibition of viral entry of flaviviruses |
| title_full_unstemmed |
Studies on the inhibition of viral entry of flaviviruses |
| title_sort |
studies on the inhibition of viral entry of flaviviruses |
| publishDate |
2011 |
| url |
https://hdl.handle.net/10356/47444 |
| _version_ |
1759857289966125056 |