Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins
268 p.
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Theses and Dissertations |
| Published: |
2011
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/47450 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| id |
sg-ntu-dr.10356-47450 |
|---|---|
| record_format |
dspace |
| spelling |
sg-ntu-dr.10356-474502023-02-28T18:36:38Z Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins Kuss, Claudia Peter Rainer Preiser School of Biological Sciences DRNTU::Science::Biological sciences::Genetics 268 p. The clinical symptoms of the parasitic disease malaria are caused by the intraerythrocytic stage of the Plasmodium spp life cycle. The invasive form of the malarial parasite for erythrocytes is the merozoite. Erythrocyte invasion is a multistep process and proteins required for this event are transcribed during the schizont stage and subsequently expressed at the merozoite stage. The merozoite is able to invade erythrocytes using a wide range of invasion pathways. Invasion pathways are determined by erythrocyte and merozoite properties. Erythrocyte characteristics and availability of erythrocyte receptors are crucial criteria for successful invasion. Each parasite clone possesses unique invasion properties: firstly the parasite clone does not necessarily express all homologues of the invasion protein family; secondly, the amount of a particular protein being expressed may vary; and thirdly some proteins are predominantly expressed over others. DOCTOR OF PHILOSOPHY (SBS) 2011-12-27T08:18:25Z 2011-12-27T08:18:25Z 2009 2009 Thesis Kuss, C. (2009). Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47450 10.32657/10356/47450 Nanyang Technological University application/pdf |
| institution |
Nanyang Technological University |
| building |
NTU Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NTU Library |
| collection |
DR-NTU |
| topic |
DRNTU::Science::Biological sciences::Genetics |
| spellingShingle |
DRNTU::Science::Biological sciences::Genetics Kuss, Claudia Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| description |
268 p. |
| author2 |
Peter Rainer Preiser |
| author_facet |
Peter Rainer Preiser Kuss, Claudia |
| format |
Theses and Dissertations |
| author |
Kuss, Claudia |
| author_sort |
Kuss, Claudia |
| title |
Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| title_short |
Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| title_full |
Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| title_fullStr |
Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| title_full_unstemmed |
Invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| title_sort |
invasion pathway switching of plasmodium falciparum reveals post-transcriptional regulation of merozoite proteins |
| publishDate |
2011 |
| url |
https://hdl.handle.net/10356/47450 |
| _version_ |
1759854459991621632 |