Study of sars-cov entry mechanism and development of protein mimetic inhibitors

195 p.

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Bibliographic Details
Main Author: Ji, Zhe
Other Authors: James P. Tam
Format: Theses and Dissertations
Published: 2011
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Online Access:https://hdl.handle.net/10356/47454
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-474542023-02-28T18:32:23Z Study of sars-cov entry mechanism and development of protein mimetic inhibitors Ji, Zhe James P. Tam School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology::Virology 195 p. The outbreak of severe acute respiratory syndrome (SARS) in 2002 and 2003 was caused by a novel and lethal virus, SARS-CoV. The existence of animal reservoirs of SARS-CoV and the threat of re-emergence of the disease intensified the urgency for clarifying its viral entry mechanism and searching for effective antiviral reagents. As one of the coronaviruses, its viral entry process is mediated by the S protein. Here, I present our study on SARS-CoV S protein and a potential approach for designing SARS-CoV viral entry inhibitors. DOCTOR OF PHILOSOPHY (SBS) 2011-12-27T08:18:50Z 2011-12-27T08:18:50Z 2010 2010 Thesis Ji, Z. (2010). Study of sars-cov entry mechanism and development of protein mimetic inhibitors. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47454 10.32657/10356/47454 Nanyang Technological University application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Science::Biological sciences::Microbiology::Virology
spellingShingle DRNTU::Science::Biological sciences::Microbiology::Virology
Ji, Zhe
Study of sars-cov entry mechanism and development of protein mimetic inhibitors
description 195 p.
author2 James P. Tam
author_facet James P. Tam
Ji, Zhe
format Theses and Dissertations
author Ji, Zhe
author_sort Ji, Zhe
title Study of sars-cov entry mechanism and development of protein mimetic inhibitors
title_short Study of sars-cov entry mechanism and development of protein mimetic inhibitors
title_full Study of sars-cov entry mechanism and development of protein mimetic inhibitors
title_fullStr Study of sars-cov entry mechanism and development of protein mimetic inhibitors
title_full_unstemmed Study of sars-cov entry mechanism and development of protein mimetic inhibitors
title_sort study of sars-cov entry mechanism and development of protein mimetic inhibitors
publishDate 2011
url https://hdl.handle.net/10356/47454
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