LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells
97 p.
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2011
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sg-ntu-dr.10356-474562023-03-03T16:05:58Z LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells Bahareh Haji Rasouliha Chen Wei Ning, William School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biotechnology 97 p. Breast cancer is known as the most common cancer in women population, especially in developed countries. Improved prognosis and effective treatment are needed to reduce the mortality of the disease. Doxorubicin, a topoisomerase II-targeting chemotherapeutic drug has been widely used to treat breast cancer. The rapidly evolved proteomics techniques, especially LC-MS/MS analysis, has been used in protein profiling in body fluids as well as cells, which provide us with a deep comprehension in drugs mechanism and patients response to the treatment. This new method can be extended in biomarker identification to improve diagnosis and monitoring of treatment. MASTER OF ENGINEERING (SCBE) 2011-12-27T08:22:00Z 2011-12-27T08:22:00Z 2010 2010 Thesis Bahareh, H. R. (2010). LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells. Master’s thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47456 10.32657/10356/47456 Nanyang Technological University application/pdf |
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DRNTU::Engineering::Chemical engineering::Biotechnology Bahareh Haji Rasouliha LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| description |
97 p. |
| author2 |
Chen Wei Ning, William |
| author_facet |
Chen Wei Ning, William Bahareh Haji Rasouliha |
| format |
Theses and Dissertations |
| author |
Bahareh Haji Rasouliha |
| author_sort |
Bahareh Haji Rasouliha |
| title |
LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| title_short |
LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| title_full |
LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| title_fullStr |
LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| title_full_unstemmed |
LC-MS/MS proteomics analysis of biomarkers in Singapore breast cancer patients on doxorubicin treatment and MCF7 breast cancer derived cells |
| title_sort |
lc-ms/ms proteomics analysis of biomarkers in singapore breast cancer patients on doxorubicin treatment and mcf7 breast cancer derived cells |
| publishDate |
2011 |
| url |
https://hdl.handle.net/10356/47456 |
| _version_ |
1759857025939931136 |