Co-delivery of hydrophobic and hydrophilic drugs from erythrocyte-PLGA nanoparticles complex

• Main Author: Tan, Tabitha Su Teng.
• Other Authors: Subramanian Venkatraman
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: http://hdl.handle.net/10356/48438
• Institution: Nanyang Technological University

This work reported the fabrication of a dual drug delivery system, where layer-by-layer polyelectrolyte-coated PLGA nanoparticles were attached onto the surface of erythrocyte via electrostatic attraction. PLGA nanoparticles were loaded with a model hydrophobic drug (ibuprofen) and coated with 3, 5...