Integrins : their roles as mechanosensors and as targets in therapeutics.

• Main Author: Tay, Xiong Sheng.
• Other Authors: Tan Suet Mien
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/49352
• Institution: Nanyang Technological University

Integrins are major adhesion proteins that mediate cell-to-cell, cell-to-matrix, or cell-to-pathogen interaction (Hynes, 2002). They are involved in angiogenesis (Silva et al., 2008), embryonic development (Spencer et al., 2004) and immunity (Smith-Garvin et al., 2009). In humans, there are 24 integ...