The role of ELKS isoforms in leptin and NF-κB signaling.

• Main Author: Woo, Yissue.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Molecular biology; DRNTU::Science::Biological sciences::Cytology
• Online Access: http://hdl.handle.net/10356/49383
• Institution: Nanyang Technological University

Obesity had been linked to a state of constant low-grade systemic inflammation, and a series of metabolic disorders, like insulin insensitivity and leptin resistance. The origin of the state of low-grade inflammation was tied to various adipocyte-secreted adipokines, including leptin and...