Fabrication of drug/polymer composite particles for pharmaceutical application

• Main Author: Poh, Kin Hwee.
• Other Authors: Li Lin
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Mechanical engineering
• Online Access: http://hdl.handle.net/10356/49407
• Institution: Nanyang Technological University

Evaporative Precipitation of Nanosuspension (EPN) was used to fabricate nanoparticles of Silymarin, a drug with low bioavailability in the human body, with the aim of enhancing its bioavailability by increasing its dissolution rate. Investigations on how varying solvent to anti-solvent ratio and dru...