Resurrecting inactive antimicrobial peptides from LPS trap.

• Main Author: Wee, Choon Chuan.
• Other Authors: Surajit Bhattacharyya
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/49607
• Institution: Nanyang Technological University

An important component on the outer membrane of Gram-negative bacteria is LPS (Lipopolysaccharide). LPS is an endotoxin, responsible for causing septic shock. It also serves as a barrier to exclude various antimicrobial agents. Recent studies on a membrane active antimicrobial peptide temporin A rev...