Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease

Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease

Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mut...

Full description

Saved in:
Bibliographic Details
Main Author: Cher, Bernard Toh Hui
Other Authors: Law Sai-Kit Alex
Format: Theses and Dissertations
Language:English
Published: 2012
Subjects:
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/50537
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-50537
record_format dspace
spelling sg-ntu-dr.10356-505372023-02-28T18:31:14Z Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease Cher, Bernard Toh Hui Law Sai-Kit Alex School of Biological Sciences DRNTU::Science::Biological sciences Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP. DOCTOR OF PHILOSOPHY (SBS) 2012-06-14T06:24:26Z 2012-06-14T06:24:26Z 2011 2011 Thesis Cher, B. T. H. (2011). Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/50537 10.32657/10356/50537 en 253 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Biological sciences
spellingShingle DRNTU::Science::Biological sciences
Cher, Bernard Toh Hui
Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
description Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP.
author2 Law Sai-Kit Alex
author_facet Law Sai-Kit Alex
Cher, Bernard Toh Hui
format Theses and Dissertations
author Cher, Bernard Toh Hui
author_sort Cher, Bernard Toh Hui
title Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
title_short Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
title_full Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
title_fullStr Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
title_full_unstemmed Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
title_sort three disparate studies on the cd18 integrin : expression and biological functions of the human cd18 integrin in health and disease
publishDate 2012
url https://hdl.handle.net/10356/50537
_version_ 1759853018429259776

Similar Items