Biophysical study of G-quadruplex structures in solution and G-wire superamolecular assembly on graphene

• Main Author: Hu, Lanying
• Other Authors: Phan Anh Tuan
• Format: Theses and Dissertations
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Biophysics
• Online Access: https://hdl.handle.net/10356/50642
• Institution: Nanyang Technological University

Guanine-rich nucleic acid sequences have a high propensity to adopt non-B DNA secondary structures like G-quadruplexes. Sequences that could potentially form G-quadruplexes are widespread throughout the genome and found to be more prominent in biologically critical regions. They may play biological...