Molecular bridging of mitotic RanGTP and Aurora B kinase in the maintenance of kinetochore-microtubule attachments

The multi-faceted RanGTPase has been implicated to be critically involved in nucleocytoplasmic transportation and cell cycle progression. However, the role of mitotic RanGTP in kinetochore-microtubule attachments at metaphase has yet to be described. Here, we report a molecular link between the mito...

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Bibliographic Details
Main Author: Lee, Yoke Peng
Other Authors: Li Hoi Yeung
Format: Theses and Dissertations
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/50646
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Institution: Nanyang Technological University
Language: English