The role of insulin receptor substrate of 53 kDa in epidermal growth factor-induced epithelial-to-mesenchymal transition.

• Main Author: Lim, Zhong Juinn.
• Other Authors: Thirumaran s/o Thanabalu
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/50885
• Institution: Nanyang Technological University

Epithelial-to-Mesenchymal transition (EMT) is a developmental programme hijacked by malignant cancer cells to acquire mesenchymal phenotype with invasive ability. Missing in Metastasis (MIM) has been shown as an important protein towards EMT suppression. However, Insulin Receptor Substrate of 53 kDa...