Studies of DNA-interacting properties of certain topological enzymes
Topoisomerases are topological enzymes that are involved in the regulation of DNA supercoiling. In this thesis, two of the type IIA topoisomerases, Topoisomerase II and DNA Gyrase, will be discussed and their DNA-interacting properties will be studied. Firstly, the change in topology of Kine...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2013
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Online Access: | http://hdl.handle.net/10356/51880 |
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Institution: | Nanyang Technological University |
Language: | English |