Leukemia inhibitory factor (LIF) regulates JAK/STAT and canonical Wnt/β-catenin signaling pathways during murine embryo implantation.

• Main Author: Yee, Li Xuan.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/52334
• Institution: Nanyang Technological University

Embryo implantation is the most critical stage in mammalian pregnancy. A key factor governing this process is the cytokine, Leukemia Inhibitory Factor (LIF). In mice, LIF acts on the uterine luminal epithelium (LE) converting it from a non-responsive epithelium to an embryo-responsive one. The LE ex...