Modulation of immune responses by genetically engineered dendritic cells

• Main Author: Wang, Qi
• Other Authors: Ruedl Christiane
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/52424
• Institution: Nanyang Technological University

Dendritic cells (DCs) are the key players in initiating and guiding innate and adaptive immune responses. In vivo targeting DCs and silencing immune responses via tolerogenic DCs are one of the most promising approaches against a variety of immune-mediated diseases. However many regulatory functions...