Analysis of a role of hypusinated eukaryotic initiation factor 5A (EIF5A) and its isoform EIF5A2 in embryonic stem cell self-renewal and differentiation.

• المؤلف الرئيسي: Lee, Su Qi.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/52472
• المؤسسة: Nanyang Technological University

Embryonic stem cells (ESCs) are pluripotent cells which are characterized by their unique ability to self-renew and generate all differentiated cell types. The polyamine regulator AMD1 (Adenosylmethionine Decarboxylase), was recently shown to be an essential self-renewal factor in ESCs (Zhang et al....