A novel method for HLA-peptide binding prediction and HLA supertype sub-typing

• Main Author: Zhao, Bing
• Other Authors: Meena Kishore Sakharkar
• Format: Theses and Dissertations
• Published: 2008
• Subjects: DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
• Online Access: https://hdl.handle.net/10356/5258
• Institution: Nanyang Technological University

Peptides binding to HLA molecules elicit specific T cell immune responses and are useful in the development of peptide vaccines and therapeutics. Thus, prediction of HLA-binding peptide is critical. Here, a prediction model is described. Many statistical and molecular mechanics models for HLA peptid...