Development of an inducible single lentiviral vector-based microRNA knockdown construct.

• Main Author: Ip, Jun Yu.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/52927
• Institution: Nanyang Technological University

MicroRNAs (miRNAs) have emerged as important post-transcriptional developmental regulators of gene expression in normal cellular processes. Perturbations in the levels of individual miRNAs or classes of miRNAs are associated with the pathogenesis of a wide range of human diseases. RNA interference (...