Structural studies of the nucleosome, assembled with different histones, DNA fragments and HMGN proteins, and derivatized with ruthenium anticancer agents

Structural studies of the nucleosome, assembled with different histones, DNA fragments and HMGN proteins, and derivatized with ruthenium anticancer agents

The nucleosome forms the basic unit of chromatin in eukaryotic cells. This compact structure made of four histone proteins and DNA serves dual interrelated functions for storage and regulation of genomic activities. Nucleosome dynamics, histone variants, histone post-translational modification, nucl...

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Bibliographic Details
Main Author: Reyhan Muhammad
Other Authors: Curtis Alexander Davey
Format: Theses and Dissertations
Language:English
Published: 2013
Subjects:
DRNTU::Science::Biological sciences::Molecular biology
DRNTU::Science::Biological sciences::Biochemistry
Online Access:https://hdl.handle.net/10356/53656
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/53656

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