Volumetric analysis of liver fibrosis.

Liver fibrosis is accumulation of extracellular matrix in the liver tissue. It occurs in response to acute or chronic liver injury. There are a large range of causes for liver fibrosis, which include viral infection, autoimmune, drug-induced, cholestatic and metabolic diseases. Liver fibrosis ultima...

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Main Author: Leong, Yong Shin.
Other Authors: Chan Chi Chiu
Format: Final Year Project
Language:English
Published: 2013
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Online Access:http://hdl.handle.net/10356/53698
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-536982023-03-03T15:39:11Z Volumetric analysis of liver fibrosis. Leong, Yong Shin. Chan Chi Chiu School of Chemical and Biomedical Engineering A*STAR SIMTech Chong Wee Keat DRNTU::Engineering::Bioengineering Liver fibrosis is accumulation of extracellular matrix in the liver tissue. It occurs in response to acute or chronic liver injury. There are a large range of causes for liver fibrosis, which include viral infection, autoimmune, drug-induced, cholestatic and metabolic diseases. Liver fibrosis ultimately leads to cirrhosis, the end-stage consequence of fibrosis within hepatic parenchyma. Cirrhosis is often characterized by presence of hepatic nodule, a hexagonal formation of extracellular matrix that encircles and isolates a portion of hepatic parenchyma. Hepatic nodule hinders blood flow within liver which detriment the normal functionality of the organ. Failure of the whole liver can occur if fibrosis becomes too extensive and by then there is no viable treatment available, except for liver transplant [1]. Liver fibrosis is a serious disease which affects hundreds of millions of patients worldwide. In the United States, cirrhosis is the most common non-neoplastic cause of death among hepatobiliary and digestive diseases which accounts for approximately 30 000 deaths per year. Furthermore, cirrhosis is one of the major causes of liver cancer which its mortality rate is raising steadily over the recent years [2]. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2013-06-07T01:27:38Z 2013-06-07T01:27:38Z 2013 2013 Final Year Project (FYP) http://hdl.handle.net/10356/53698 en Nanyang Technological University 73 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Bioengineering
spellingShingle DRNTU::Engineering::Bioengineering
Leong, Yong Shin.
Volumetric analysis of liver fibrosis.
description Liver fibrosis is accumulation of extracellular matrix in the liver tissue. It occurs in response to acute or chronic liver injury. There are a large range of causes for liver fibrosis, which include viral infection, autoimmune, drug-induced, cholestatic and metabolic diseases. Liver fibrosis ultimately leads to cirrhosis, the end-stage consequence of fibrosis within hepatic parenchyma. Cirrhosis is often characterized by presence of hepatic nodule, a hexagonal formation of extracellular matrix that encircles and isolates a portion of hepatic parenchyma. Hepatic nodule hinders blood flow within liver which detriment the normal functionality of the organ. Failure of the whole liver can occur if fibrosis becomes too extensive and by then there is no viable treatment available, except for liver transplant [1]. Liver fibrosis is a serious disease which affects hundreds of millions of patients worldwide. In the United States, cirrhosis is the most common non-neoplastic cause of death among hepatobiliary and digestive diseases which accounts for approximately 30 000 deaths per year. Furthermore, cirrhosis is one of the major causes of liver cancer which its mortality rate is raising steadily over the recent years [2].
author2 Chan Chi Chiu
author_facet Chan Chi Chiu
Leong, Yong Shin.
format Final Year Project
author Leong, Yong Shin.
author_sort Leong, Yong Shin.
title Volumetric analysis of liver fibrosis.
title_short Volumetric analysis of liver fibrosis.
title_full Volumetric analysis of liver fibrosis.
title_fullStr Volumetric analysis of liver fibrosis.
title_full_unstemmed Volumetric analysis of liver fibrosis.
title_sort volumetric analysis of liver fibrosis.
publishDate 2013
url http://hdl.handle.net/10356/53698
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