Studying pharmacokinetic parameters of engineered Bradykinin drugs (SFBK and BKSF) in mice.

• Main Author: Li, GuoAn.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/53703
• Institution: Nanyang Technological University

The aim of this study was to examine the pharmacokinetic parameters of engineered bradykinin drugs (SFBK and BKSF) using oral delivery method in mice. In the previous study, we have shown that the SFBK drug have pH, pepsin and trypsin stability. BKSF drug have pH and pepsin stability but lack of try...