Hepatogenic differentiation of induced pluripotent stem cells and embryonic stem cells in 3D hydrogel system.

• Main Author: Liao, Yanwan.
• Other Authors: Wang Dongan
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/54306
• Institution: Nanyang Technological University

Liver transplantation is the only effective treatment of end-stage liver disease, but it is limited by the sustained shortage of donor organ with the growing demand. Primary hepatocytes may be the first choice for liver regeneration, however, it only has finite source and rapidly loses phenotype whe...