Metabolic engineering for the optimal production of Taxol (Paclitaxel) - an efficient anticancer drug (focusing on upstream pathways for isoprenoid accumulation).

Taxol is one of the most important and active chemotherapeutic agents for clinical treatment of cancers (including ovarian, breast bladder, prostate, and lung cancers), since taxol is an anti-proliferative agent that inhibits cancer cell division. However, the separation from pacific yew trees is th...

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Bibliographic Details
Main Author: Ng, James Shizhao.
Other Authors: Song Hao
Format: Theses and Dissertations
Language:English
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10356/54323
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Institution: Nanyang Technological University
Language: English