Hepatitis B virus drug resistance mutation detection by pyrosequencing method

• Main Author: Toh, Kim Pern.
• Other Authors: Sridhar Idapalapati
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/54551
• Institution: Nanyang Technological University

Monitoring of drug resistance mutations in Hepatitis B virus (HBV) is critical for the management of chronic HBV infection treatment. It is important to use a system that is sensitive and specific in its detection. In this report, we proposed pyrosequencing as a method for the detection of 13 mutati...