Hepatitis B virus drug resistance mutation detection by pyrosequencing method

• المؤلف الرئيسي: Toh, Kim Pern.
• مؤلفون آخرون: Sridhar Idapalapati
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Engineering::Bioengineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/54551

Monitoring of drug resistance mutations in Hepatitis B virus (HBV) is critical for the management of chronic HBV infection treatment. It is important to use a system that is sensitive and specific in its detection. In this report, we proposed pyrosequencing as a method for the detection of 13 mutati...