Identification of epigenetic regulators cooperating with oncogene yorkie and notch in promoting tumorigenesis and metastasis in drosophila melanogaster

• Main Author: Qi, Le
• Other Authors: Hector Herranz
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/54638
• Institution: Nanyang Technological University

Epigenetic regulators are emerging as cooperating factors that promote the activity of oncogenes in tumorigenesis and metastasis. In this study, we screened 19 epigenetic regulators in Polycomb group genes, Trithorax group genes, other related histone modifiers and chromatin remodeling complexes for...