Optimization of culture conditions in HS5 stroma suppported hematopoietic culture.

• Main Author: Goh, Carlye Qian Ling.
• Other Authors: Mayasari Lim
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/54647
• Institution: Nanyang Technological University

Stroma cells play an essential role in the bone marrow niche, the environment where hematopoietic cells and progenitors self-renew and differentiate into multiple lineage. A simple 2D model comprising of a monolayer of stroma cells is being used to produce platelets. This study aims to optimize the...