Comprehensive mapping of post-translational modifications of progesterone receptor (PR) and functional analysis of novel methylation and acetylation of PR.

• Main Author: Chung, Hwa Hwa.
• Other Authors: Lin Chun Ling Valerie
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/54720
• Institution: Nanyang Technological University

There is increasing evidence that progesterone is involved in breast cancer progression. The progesterone receptor (PR) is a member of the nuclear receptor superfamily. Its activity is regulated at multiple levels of the receptor activation pathway including receptor maturation, ligand-bind...