Characterization of kindlin3 in Integrin functions

• Main Author: Feng, Chen
• Other Authors: Tan Suet Mien
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/54828
• Institution: Nanyang Technological University

Integrins are heterodimeric cell adhesion molecules that are involved in many biological processes. Integrin ligand-binding requires its activation by the FERM (4.1 ezrin radixin moesin)-domain-containing cytoplasmic protein talin 1/2. Recently, another family of FERM-domain-containing cytoplasmic p...