NMR solution structure of C2 domain of MFG-E8 and insights into its recognition with phosphatidylserine

MFG-E8 (also known as lactadherin), which is a secreted glycoprotein from a variety of cell types, possesses two EGF domains and tandem C domains with sequence homology to that of blood coagulation proteins factor V and factor VIII. MFG-E8 binds to phosphatidylserine (PS) in membranes with high affi...

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Bibliographic Details
Main Author: Li, Baihong
Other Authors: Yoon Ho Sup
Format: Theses and Dissertations
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/54855
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Institution: Nanyang Technological University
Language: English