NMR solution structure of C2 domain of MFG-E8 and insights into its recognition with phosphatidylserine
MFG-E8 (also known as lactadherin), which is a secreted glycoprotein from a variety of cell types, possesses two EGF domains and tandem C domains with sequence homology to that of blood coagulation proteins factor V and factor VIII. MFG-E8 binds to phosphatidylserine (PS) in membranes with high affi...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/54855 |
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Institution: | Nanyang Technological University |
Language: | English |