Structural modeling of LAG-3 protein and immunoglobulin domains

• Main Author: Lai, Marcel Chang Long
• Other Authors: Kwoh Chee Keong
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: http://hdl.handle.net/10356/59087
• Institution: Nanyang Technological University

Lymphocyte-activation gene 3 (LAG3) is a protein that limits the activity of T-cells, which down regulates the immune system. The protein functions can be determined from its structure. However, there is currently no available structure of LAG3 in any database. In order to fully understand its funct...