Computational approaches for disease gene identification

Identifying disease genes from the human genome is a crucial but challenging task in the area of bioinformatics research and medical health. In wet-lab experiments, disease genes are identified using mutation analysis, which is very expensive and labor intensive. In this thesis, we proposed novel co...

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Main Author: Yang, Peng
Other Authors: Ng See-Kiong
Format: Theses and Dissertations
Language:English
Published: 2014
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Online Access:https://hdl.handle.net/10356/59238
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-592382023-03-04T00:45:54Z Computational approaches for disease gene identification Yang, Peng Ng See-Kiong Kwoh Chee Keong Li Xiaoli School of Computer Engineering Bioinformatics Research Centre DRNTU::Engineering::Computer science and engineering::Information systems::Information systems applications Identifying disease genes from the human genome is a crucial but challenging task in the area of bioinformatics research and medical health. In wet-lab experiments, disease genes are identified using mutation analysis, which is very expensive and labor intensive. In this thesis, we proposed novel computational approaches to prioritize and identify disease genes. The experimental results show that our work is more robust and accurate than other state-of-the-the-art techniques for disease gene identification. DOCTOR OF PHILOSOPHY (SCE) 2014-04-28T02:05:13Z 2014-04-28T02:05:13Z 2014 2014 Thesis Yang, P. (2014). Computational approaches for disease gene identification. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/59238 10.32657/10356/59238 en 179 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Computer science and engineering::Information systems::Information systems applications
spellingShingle DRNTU::Engineering::Computer science and engineering::Information systems::Information systems applications
Yang, Peng
Computational approaches for disease gene identification
description Identifying disease genes from the human genome is a crucial but challenging task in the area of bioinformatics research and medical health. In wet-lab experiments, disease genes are identified using mutation analysis, which is very expensive and labor intensive. In this thesis, we proposed novel computational approaches to prioritize and identify disease genes. The experimental results show that our work is more robust and accurate than other state-of-the-the-art techniques for disease gene identification.
author2 Ng See-Kiong
author_facet Ng See-Kiong
Yang, Peng
format Theses and Dissertations
author Yang, Peng
author_sort Yang, Peng
title Computational approaches for disease gene identification
title_short Computational approaches for disease gene identification
title_full Computational approaches for disease gene identification
title_fullStr Computational approaches for disease gene identification
title_full_unstemmed Computational approaches for disease gene identification
title_sort computational approaches for disease gene identification
publishDate 2014
url https://hdl.handle.net/10356/59238
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