Gag and protease co-evolution modeling for HIV-1

• Main Author: Wang, Junjie
• Other Authors: Kwoh Chee Keong
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Computer science and engineering::Computing methodologies::Simulation and modeling
• Online Access: http://hdl.handle.net/10356/59251
• Institution: Nanyang Technological University

Gag and Protease play important roles in the lifecycle of the HIV-1 virus. Protease is the viral enzyme that cleaves Gag to form functional Gag subunits during the viral maturation. To interfere with the maturation of the HIV virus, Protease Inhibitors or drugs are used to inhibit the Gag-cleaving f...