Gag and protease co-evolution modeling for HIV-1

• 主要作者: Wang, Junjie
• 其他作者: Kwoh Chee Keong
• 格式: Final Year Project
• 語言: English
• 出版: 2014
• 主題: DRNTU::Engineering::Computer science and engineering::Computing methodologies::Simulation and modeling
• 在線閱讀: http://hdl.handle.net/10356/59251
• 機構: Nanyang Technological University

Gag and Protease play important roles in the lifecycle of the HIV-1 virus. Protease is the viral enzyme that cleaves Gag to form functional Gag subunits during the viral maturation. To interfere with the maturation of the HIV virus, Protease Inhibitors or drugs are used to inhibit the Gag-cleaving f...