Protein dimer interfaces : ligands, sidechains, hot spots and binding

• Main Author: Lei, Li
• Other Authors: Gan Gah Kok, Jacob
• Format: Theses and Dissertations
• Published: 2008
• Subjects: DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
• Online Access: https://hdl.handle.net/10356/5990
• Institution: Nanyang Technological University

Protein dimer interactions (homodimers and heterodimers) are common in molecular catalysis and regulation. Prediction of interaction sites or interaction partners from sequence is challenging. The significance of interface ligands, sidechain-sidechain prevalence at the interfaces, “hot spot” interfa...