Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties

In this study, Aloe Vera extract has been explored as a pharmacologic additive in tissue preservation medium to prolong the “safe” ischemia time. Aortic (AV) and pulmonary (PV) valve leaflets were harvested from freshly procured porcine hearts and then subjected to preservation treatment of differen...

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Main Author:	Bai, Lin
Other Authors:	Chong, Chuh Khiun
Format:	Theses and Dissertations
Published:	2008
Subjects:	DRNTU::Engineering::Bioengineering
Online Access:	http://hdl.handle.net/10356/6018
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Institution:	Nanyang Technological University

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spelling	sg-ntu-dr.10356-60182023-03-11T17:01:56Z Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties Bai, Lin Chong, Chuh Khiun School of Mechanical and Aerospace Engineering DRNTU::Engineering::Bioengineering In this study, Aloe Vera extract has been explored as a pharmacologic additive in tissue preservation medium to prolong the “safe” ischemia time. Aortic (AV) and pulmonary (PV) valve leaflets were harvested from freshly procured porcine hearts and then subjected to preservation treatment of different Aloe Vera extract concentrations and ischemic time of 0, 18, and 60 hours. Uniaxial mechanical test and MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay were performed to assess the mechanical properties and cell viability, respectively. The result showed that the preservation time (P<0.05) has a significant effect on the Failure Strain of AV and the Failure Load of PV, as well as the OD of PV. Master of Science (Biomedical Engineering) 2008-09-17T11:04:52Z 2008-09-17T11:04:52Z 2005 2005 Thesis http://hdl.handle.net/10356/6018 Nanyang Technological University application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
topic	DRNTU::Engineering::Bioengineering
spellingShingle	DRNTU::Engineering::Bioengineering Bai, Lin Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
description	In this study, Aloe Vera extract has been explored as a pharmacologic additive in tissue preservation medium to prolong the “safe” ischemia time. Aortic (AV) and pulmonary (PV) valve leaflets were harvested from freshly procured porcine hearts and then subjected to preservation treatment of different Aloe Vera extract concentrations and ischemic time of 0, 18, and 60 hours. Uniaxial mechanical test and MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay were performed to assess the mechanical properties and cell viability, respectively. The result showed that the preservation time (P<0.05) has a significant effect on the Failure Strain of AV and the Failure Load of PV, as well as the OD of PV.
author2	Chong, Chuh Khiun
author_facet	Chong, Chuh Khiun Bai, Lin
format	Theses and Dissertations
author	Bai, Lin
author_sort	Bai, Lin
title	Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
title_short	Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
title_full	Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
title_fullStr	Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
title_full_unstemmed	Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
title_sort	effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
publishDate	2008
url	http://hdl.handle.net/10356/6018
_version_	1761781838647394304

Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties

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