Establishing a scientific visualization framework to assess drug-induced cardiotoxicity using transgenic zebrafish

• Main Author: Ismail Osman
• Other Authors: Vladmir Korzh
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/60260
• Institution: Nanyang Technological University

Drug-induced cardiotoxicity is the leading cause of drug withdrawals from the market. Zebrafish embryos and larvae are suitable as an alternative screening model that can bridge the gap between in vivo mammalian models and in vitro cell-based models, for the early screening of potentially cardiotoxi...