Activation and regulation of IL-1β family of cytokines by EV71 infection

• Main Author: Aw, Ashley Jong Ghut
• Other Authors: Liu Ding Xiang
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/60262
• Institution: Nanyang Technological University

Severe cases of hand, foot and mouth disease (HFMD) are usually caused by Enterovirus 71 (EV71) and linked to elevated levels of cytokines. In this study, we first tested the ability of EV71 (BrCr and WD strain) in infecting differentiated monocyte lymphoma (U937) cells, epithelial lung cancer (A549...